Glutathione Peroxidase 4 is associated with Neuromelanin in Substantia Nigra and Dystrophic Axons in Putamen of Parkinson's brain

P. Bellinger, Frederick; T. Bellinger, Miyoko; A. Seale, Lucia; S. Takemoto, Andrea; V. Raman, Arjun; Miki, Takanori; Manning-Bog, Amy; J. Berry, Marla; R. White, Lon; Ross, George

doi:10.1186/1750-1326-6-8

Public

Glutathione Peroxidase 4 is associated with Neuromelanin in Substantia Nigra and Dystrophic Axons in Putamen of Parkinson's brain

Published in Molecular Neurodegeneration • Jan 1, 2011

Authors:

Frederick P. Bellinger

Miyoko T. Bellinger

Lucia A. Seale

Abstract

BACKGROUND: Parkinson's disease is a neurodegenerative disorder characterized pathologically by the loss of nigrostriatal dopamine neurons that project from the substantia nigra in the midbrain to the putamen and caudate nuclei, leading to the clinical features of bradykinesia, rigidity, and rest tr...

Subject

Substantia nigra

Neuromelanin

Putamen

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