Genetic Susceptibility to Asthma — Bronchial Hyperresponsiveness Coinherited with a Major Gene for Atopy

S. Postma, Dirkje; R. Bleecker, Eugene; J. Amelung, Pamela; J. Holroyd, Kenneth; Xu, Jianfeng; Panhuysen, Carolien; A. Meyers, Deborah; C. Levitt, Roy

doi:10.1056/nejm199510053331402

Public

Genetic Susceptibility to Asthma — Bronchial Hyperresponsiveness Coinherited with a Major Gene for Atopy

Published in New England Journal of Medicine • Oct 5, 1995

Authors:

Dirkje S. Postma

Eugene R. Bleecker

Pamela J. Amelung

Abstract

BACKGROUND: Bronchial hyperresponsiveness, a risk factor for asthma, consists of a heightened bronchoconstrictor response to a variety of stimuli. The condition has a heritable component and is closely related to serum IgE levels and airway inflammation. The basis for these relations is unknown, as ...

Subject

Atopy

Bronchial hyperresponsiveness

Medicine

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