Analysis of Circulating Tumor DNA to Monitor Metastatic Breast Cancer

Dawson, Sarah‐Jane; W.Y. Tsui, Dana; Murtaza, Muhammed; Biggs, Heather; M. Rueda, Oscar; Chin, Suet‐Feung; Dunning, Mark; Gale, Davina; Forshew, Tim; Mahler‐Araujo, Betania; Rajan, Sabrina; Humphray, Sean; Becq, Jennifer; Halsall, David; Wallis, Matthew; Bentley, David; Caldas, Carlos; Rosenfeld, Nitzan

doi:10.1056/nejmoa1213261

Public

Analysis of Circulating Tumor DNA to Monitor Metastatic Breast Cancer

Published in New England Journal of Medicine • Mar 13, 2013

Authors:

Sarah‐Jane Dawson

Dana W.Y. Tsui

Muhammed Murtaza

Abstract

BACKGROUND: The management of metastatic breast cancer requires monitoring of the tumor burden to determine the response to treatment, and improved biomarkers are needed. Biomarkers such as cancer antigen 15-3 (CA 15-3) and circulating tumor cells have been widely studied. However, circulating cell-...

Subject

Breast cancer

Circulating tumor cell

Metastatic breast cancer

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