Oral Capecitabine Compared With Intravenous Fluorouracil Plus Leucovorin in Patients With Metastatic Colorectal Cancer: Results of a Large Phase III Study

Van Cutsem, Eric; Twelves, Chris; Cassidy, Jim; Allman, David; Bajetta, Emilio; Boyer, Michael; Bugat, R.; Findlay, M; Frings, S.; K. Jahn, Michaela; McKendrick, Joe; Osterwalder, B; Pérez-Manga, G.; Rosso, Riccardo; Rougier, Philippe; Schmiegel, Wolff; Seitz, Jean‐François; Thompson, Paul; María Viéitez, José; Weitzel, Christof; Harper, Peter

doi:10.1200/jco.2001.19.21.4097

Public

Oral Capecitabine Compared With Intravenous Fluorouracil Plus Leucovorin in Patients With Metastatic Colorectal Cancer: Results of a Large Phase III Study

Published in Journal of Clinical Oncology • Nov 1, 2001

Authors:

Eric Van Cutsem

Chris Twelves

Jim Cassidy

Abstract

PURPOSE: To compare the efficacy and safety of orally administered capecitabine (Xeloda; Roche Laboratories, Inc, Nutley, NJ), a novel fluoropyrimidine carbamate designed to mimic continuous fluorouracil (5-FU) infusion but with preferential activation at the tumor site, with that of intravenous (IV...

Subject

Capecitabine

Medicine

Neutropenia

Finding related papers...

Discussions

(0)

No comments yet

Be the first to share your thoughts!