Establishment of a Pancreatic β Cell Line That Retains Glucose-Inducible Insulin Secretion: Special Reference to Expression of Glucose Transporter Isoforms*

Miyazaki, Jun‐ichi; Araki, Kimi; Yamato, Eiji; Ikegami, Hiroshi; Asano, Tomoichiro; Shibasaki, Yoshikazu; Oka, Yoshitomo; Yamamura, Ken–ichi

doi:10.1210/endo-127-1-126

Public

Establishment of a Pancreatic β Cell Line That Retains Glucose-Inducible Insulin Secretion: Special Reference to Expression of Glucose Transporter Isoforms*

Published in Endocrinology • Jul 1, 1990

Authors:

Jun‐ichi Miyazaki

Kimi Araki

Eiji Yamato

Abstract

Two cell lines have been established from insulinomas obtained by targeted expression of the simian virus 40 T antigen gene in transgenic mice. These cell lines, designated MIN6 and MIN7, produce insulin and T antigen and have morphological characteristics of pancreatic beta cells. MIN6 cells exhibi...

Subject

Endocrinology

Internal medicine

Cell culture

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