Human Breast Cancer: Correlation of Relapse and Survival with Amplification of the HER-2/
                    <i>neu</i>
                    Oncogene

J. Slamon, Dennis; M. Clark, Gary; G. Wong, Steven; J. Levin, Wendy; Ullrich, Axel; L. McGuire, William

doi:10.1126/science.3798106

Public

Human Breast Cancer: Correlation of Relapse and Survival with Amplification of the HER-2/ neu Oncogene

Shared by NobleBlocks on Jan 9, 1987 • 12:00 AM UTC

Authors:

Dennis J. Slamon

Gary M. Clark

Steven G. Wong

Abstract

The HER-2/ neu oncogene is a member of the erb B-like oncogene family, and is related to, but distinct from, the epidermal growth factor receptor. This gene has been shown to be amplified in human breast cancer cell lines. In the current study, alterations of the gene in 189 primary human breast can...

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