Development of a cross-platform biomarker signature to detect renal transplant tolerance in humans

Sagoo, Pervinder; Perucha, Esperanza; Sawitzki, Birgit; Tomiuk, Stefan; A. Stephens, David; Miqueu, Patrick; Chapman, Stephanie; Craciun, Ligia; Sergeant, Ruhena; Brouard, Sophie; Rovis, Flavia; Jimenez, Elvira; Ballow, A.; Giral, Magali; Rebollo‐Mesa, Irene; Le Moine, Alaín; Braudeau, Cécile; Hilton, Rachel; Gerstmayer, Bernhard; Bourcier, Katarzyna; Sharif, Adnan; Krajewska, Magdalena; M. Lord, Graham; S. Roberts, Ian; Goldman, Michel; J. Wood, Kathryn; A. Newell, Kenneth; Seyfert‐Margolis, Vicki; Ν. Warrens, Anthony; Janßen, Uwe; Volk, Hans‐Dieter; Soulillou, Jean‐Paul; P. Hernández-Fuentes, María; I. Lechler, Robert

doi:10.1172/jci39922

Public

Development of a cross-platform biomarker signature to detect renal transplant tolerance in humans

Published in Journal of Clinical Investigation • May 24, 2010

Authors:

Pervinder Sagoo

Esperanza Perucha

Birgit Sawitzki

Abstract

Identifying transplant recipients in whom immunological tolerance is established or is developing would allow an individually tailored approach to their posttransplantation management. In this study, we aimed to develop reliable and reproducible in vitro assays capable of detecting tolerance in rena...

Subject

Biomarker

Transplantation

Medicine

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