Short, Full-Dose Adjuvant Chemotherapy in High-Risk Adult Soft Tissue Sarcomas: A Randomized Clinical Trial From the Italian Sarcoma Group and the Spanish Sarcoma Group

Gronchi, Alessandro; Frustaci, S.; Mercuri, Mario; Martín‐Broto, Javier; López–Pousa, Antonio; Verderio, Paolo; Mariani, Lidia; Valagussa, Pinuccia; Miceli, Rosalba; Stacchiotti, Silvia; Paolo Dei Tos, Angelo; De Paoli, Antonino; Longhi, Alessandra; Poveda, Andrés; Quagliuolo, Vittorio; Comandone, Alessandro; G. Casali, Paolo; Picci, Piero

doi:10.1200/jco.2011.37.7218

Public

Short, Full-Dose Adjuvant Chemotherapy in High-Risk Adult Soft Tissue Sarcomas: A Randomized Clinical Trial From the Italian Sarcoma Group and the Spanish Sarcoma Group

Published in Journal of Clinical Oncology • Feb 7, 2012

Authors:

Alessandro Gronchi

S. Frustaci

Mario Mercuri

Abstract

PURPOSE: A previous randomized clinical trial by the Italian Sarcoma Group (ISG) had shown a survival benefit of adjuvant chemotherapy (CT) in high-risk extremity soft tissue sarcoma (STS). However, the dose-intensity of the last two cycles was suboptimal. We then undertook a multicentric internatio...

Subject

Medicine

Sarcoma

Soft tissue sarcoma

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