Interferon- Release Assays Improve the Diagnosis of Tuberculosis and Nontuberculous Mycobacterial Disease in Children in a Country with a Low Incidence of Tuberculosis

Detjen, Anne; Keil, Thomas; Roll, Stephanie; Hauer, B.; Mauch, H.; Wahn, Ulrich; Magdorf, K.

doi:10.1086/519266

Public

Interferon- Release Assays Improve the Diagnosis of Tuberculosis and Nontuberculous Mycobacterial Disease in Children in a Country with a Low Incidence of Tuberculosis

Published in Clinical Infectious Diseases • Jun 29, 2007

Authors:

Anne Detjen

Thomas Keil

Stephanie Roll

Abstract

BACKGROUND: Diagnosis of childhood tuberculosis (TB) is challenging. The widely used tuberculin skin test (TST) may produce -positive results because of cross-reactivity with nontuberculous mycobacteria or bacille Calmette-Guerin vaccination, resulting in unnecessary treatment. Two recently develope...

Subject

Medicine

Nontuberculous mycobacteria

Tuberculosis

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