Estrogen Promotes Early Osteoblast Differentiation and Inhibits Adipocyte Differentiation in Mouse Bone Marrow Stromal Cell Lines that Express Estrogen Receptor (ER) α or β

Okazaki, Ryo; Inoue, Daisuke; Shibata, Minako; Saika, Mieko; Kido, Shinsuke; Ooka, H; Tomiyama, Hirofumi; Sakamoto, Yoshikazu; Matsumoto, Toshio

doi:10.1210/endo.143.6.8854

Public

Estrogen Promotes Early Osteoblast Differentiation and Inhibits Adipocyte Differentiation in Mouse Bone Marrow Stromal Cell Lines that Express Estrogen Receptor (ER) α or β

Published in Endocrinology • Jun 1, 2002

Authors:

Ryo Okazaki

Daisuke Inoue

Minako Shibata

Abstract

Although cells of the osteoblast lineage express functional ERs, direct effects of estrogen on bone formation remain obscure. In the present study, we have investigated estrogen effects on osteoblastic and adipocytic differentiation from a mouse bone marrow stromal cell line, ST-2, which had been ma...

Subject

Endocrinology

Internal medicine

Osteoblast

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