CRISPR/Cas9-mediated gene editing in human tripronuclear zygotes

Liang, Puping; Xu, Yanwen; Zhang, Xiya; Ding, Chenhui; Huang, Rui; Zhang, Zhen; Lv, Jie; Xie, Xiaowei; Chen, Yuxi; Li, Yujing; Sun, Ying; Bai, Yaofu; Songyang, Zhou; Ma, Wenbin; Zhou, Canquan; Huang, Junjiu

doi:10.1007/s13238-015-0153-5

Public

CRISPR/Cas9-mediated gene editing in human tripronuclear zygotes

Published in Protein & Cell • Apr 17, 2015

Authors:

Puping Liang

Yanwen Xu

Xiya Zhang

Abstract

Genome editing tools such as the clustered regularly interspaced short palindromic repeat (CRISPR)-associated system (Cas) have been widely used to modify genes in model systems including animal zygotes and human cells, and hold tremendous promise for both basic research and clinical applications. T...

Subject

CRISPR

Genome editing

Cas9

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