Adipose-Derived Mesenchymal Stem Cell Protects Kidneys against Ischemia-Reperfusion Injury through Suppressing Oxidative Stress and Inflammatory Reaction

Chen, Yen-Ta; Sun, Cheuk‐Kwan; Lin, Yu‐Chun; Chang, Li‐Teh; Chen, Yung‐Lung; Tsai, Tzu‐Hsien; Chung, Sheng‐Ying; Chua, Sarah; H. Kao, Y.; Yen, Chia‐Hung; Shao, Pei‐Lin; Chang, Kuan‐Cheng; Leu, Steve; Yip, Hon‐Kan

doi:10.1186/1479-5876-9-51

Public

Adipose-Derived Mesenchymal Stem Cell Protects Kidneys against Ischemia-Reperfusion Injury through Suppressing Oxidative Stress and Inflammatory Reaction

Published in Journal of Translational Medicine • May 5, 2011

Authors:

Yen-Ta Chen

Cheuk‐Kwan Sun

Yu‐Chun Lin

Abstract

BACKGROUND: Reactive oxygen species are important mediators exerting toxic effects on various organs during ischemia-reperfusion (IR) injury. We hypothesized that adipose-derived mesenchymal stem cells (ADMSCs) protect the kidney against oxidative stress and inflammatory stimuli in rat during renal ...

Subject

Oxidative stress

Reperfusion injury

Glutathione peroxidase

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