Epidermolysis bullosa acquisita antigen is the globular carboxyl terminus of type VII procollagen.

T. Woodley, David; E. Burgeson, Robert; P. Lunstrum, Gregory; Bruckner‐Tuderman, Leena; J. Reese, Melinda; A. Briggaman, Robert

doi:10.1172/jci113373

Public

Epidermolysis bullosa acquisita antigen is the globular carboxyl terminus of type VII procollagen.

Published in Journal of Clinical Investigation • Mar 1, 1988

Authors:

David T. Woodley

Robert E. Burgeson

Gregory P. Lunstrum

Abstract

Epidermolysis bullosa acquisita (EBA) is a severe, chronic blistering disease of the skin. EBA patients have circulating and tissue-bound autoantibodies to a large (Mr = 290,000) macromolecule that is localized within the basement membrane zone between the epidermis and dermis of skin, the site of b...

Subject

Epidermolysis bullosa acquisita

Epidermolysis bullosa

Immunoelectron microscopy

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