Use of Arsenic Trioxide (As2O3 ) in the Treatment of Acute Promyelocytic Leukemia (APL): II. Clinical Efficacy and Pharmacokinetics in Relapsed Patients

Shen, Zhixiang; Chen, Guoqiang; Ni, Jian-Hua; Li, Xiu-Shong; Xiong, Shu-Min; Qiu, Qian-Yao; Zhu, Jun; Tang, Wei; Sun, Guan-Lin; Yang, Kan-Qi; Chen, Yu; Zhou, Li; Fang, Zhi-Wen; Wang, Yanting; Ma, Jun; Zhang, Peng; Zhang, Ting-Dong; Chen, Sai‐Juan; Chen, Zhu; Wang, Zhenyi

doi:10.1182/blood.v89.9.3354

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Use of Arsenic Trioxide (As2O3 ) in the Treatment of Acute Promyelocytic Leukemia (APL): II. Clinical Efficacy and Pharmacokinetics in Relapsed Patients

Published in Blood • May 1, 1997

Authors:

Zhixiang Shen

Guoqiang Chen

Jian-Hua Ni

Abstract

The therapeutic effect of arsenic trioxide (As2O3) in the treatment of acute promyelocytic leukemia (APL) was evaluated among 15 APL patients at relapse after all-trans retinoic acid (ATRA) induced and chemotherapy maintained complete remission (CR). As2O3 was administered intravenously at the dose ...

Subject

Arsenic trioxide

Acute promyelocytic leukemia

Pharmacokinetics

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