Open-Source Genomic Analysis of Shiga-Toxin–Producing<i>E. coli</i>O104:H4

Rohde, Holger; Qin, Junjie; Cui, Yujun; Li, Dongfang; J. Loman, Nicholas; Hentschke, Moritz; Chen, Wen‐Tong; Pu, Fei; Peng, Yangqing; Li, Junhua; Xi, Feng; Li, Shenghui; Li, Yin; Zhang, Zhaoxi; Yang, Xianwei; Zhao, Meiru; Wang, Peng; Guan, Yuanlin; Cen, Zhong; Zhao, Xiangna; Christner, Martin; Kobbe, Robin; Loos, Sebastian; Oh, Jun; Yang, Liang; Danchin, Antoine; F. Gao, George; Song, Yajun; Li, Yingrui; Yang, Huanming; Wang, Jian; Xu, Jianguo; J. Pallen, Mark; Wang, Jun; Aepfelbacher, Martin; Yang, Ruifu

doi:10.1056/nejmoa1107643

Public

Open-Source Genomic Analysis of Shiga-Toxin–ProducingE. coliO104:H4

Published in New England Journal of Medicine • Jul 27, 2011

Authors:

Holger Rohde

Junjie Qin

Yujun Cui

Abstract

An outbreak caused by Shiga-toxin–producing Escherichia coli O104:H4 occurred in Germany in May and June of 2011, with more than 3000 persons infected. Here, we report a cluster of cases associated with a single family and describe an open-source genomic analysis of an isolate from one member of the...

Subject

Outbreak

Escherichia coli

Microbiology

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