Double-blind, placebo-controlled trial of pirfenidone in patients with idiopathic pulmonary fibrosis.

A, Azuma; T, Nukiwa; E, Tsuboi; M, Suga; S, Abe; K, Nakata; Y, Taguchi; S, Nagai; H, Itoh; M, Ohi; A, Sato; S, Kudoh

doi:10.1164/rccm.200404-571oc

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Double-blind, placebo-controlled trial of pirfenidone in patients with idiopathic pulmonary fibrosis.

Shared by NobleBlocks on Jan 21, 2005 • 12:00 AM UTC

Authors:

Azuma A

Nukiwa T

Tsuboi E

Abstract

Idiopathic pulmonary fibrosis (IPF) is a fatal disorder without an effective therapy to date. In a double-blind, randomized, placebo-controlled trial, 107 patients were prospectively evaluated for efficacy of a novel compound, pirfenidone. The difference in the change in the lowest oxygen saturation...

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