Embryonic stem cells can form germ cells
                    <i>in vitro</i>

Toyooka, Yayoi; Tsunekawa, Naoki; Akasu, Ryuko; Noce, Toshiaki

doi:10.1073/pnas.1932826100

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Embryonic stem cells can form germ cells in vitro

Shared by NobleBlocks on Sep 22, 2003 • 12:00 AM UTC

Authors:

Yayoi Toyooka

Naoki Tsunekawa

Ryuko Akasu

Abstract

Knock-in embryonic stem (ES) cells, in which GFP or lacZ was expressed from the endogenous mouse vasa homolog ( Mvh ), which is specifically expressed in differentiating germ cells, were used to visualize germ cell production during in vitro differentiation. The appearance of MVH-positive germ cells...

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