Effect of Heart Rate Control With Esmolol on Hemodynamic and Clinical Outcomes in Patients With Septic Shock

Morelli, Andrea; Ertmer, Christian; Westphal, Martin; Rehberg, Sebastian; Kampmeier, Tim; Ligges, Sandra; Orecchioni, Alessandra; D’Egidio, Annalia; D''Ippoliti, Fiorella; Raffone, C; Venditti, Mario; Guarracino, Fabio; Girardis, Massimo; Tritapepe, Luigi; Pietropaoli, P; Mebazaa, Alexander; Singer, Mervyn

doi:10.1001/jama.2013.278477

Public

Effect of Heart Rate Control With Esmolol on Hemodynamic and Clinical Outcomes in Patients With Septic Shock

Published in JAMA • Oct 9, 2013

Authors:

Andrea Morelli

Christian Ertmer

Martin Westphal

Abstract

IMPORTANCE: β-Blocker therapy may control heart rate and attenuate the deleterious effects of β-adrenergic receptor stimulation in septic shock. However, β-Blockers are not traditionally used for this condition and may worsen cardiovascular decompensation related through negative inotropic and hypot...

Subject

Medicine

Esmolol

Septic shock

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