Safety and Efficacy of a Pentavalent Human–Bovine (WC3) Reassortant Rotavirus Vaccine

Vesikari, Timo; O. Matson, David; H. Dennehy, Penelope; Van Damme, Pierre; Santosham, Mathuram; Rodriguez, Zoe; J. Dallas, Michael; F. Heyse, Joseph; G. Goveia, Michelle; Black, Steven; R. Shinefield, Henry; D C Christie, C; Ylitalo, Samuli; Itzler, Robbin; L. Coia, Michele; Onorato, Matthew; Adeyi, Ben; S. Marshall, Gary; Gothefors, Leif; Campens, Dirk; Karvonen, Aino; Watt, James; L. O’Brien, Katherine; J. DiNubile, Mark; F. Clark, H.; W. Boslego, John; A. Offit, Paul; M. Heaton, Penny

doi:10.1056/nejmoa052664

Public

Safety and Efficacy of a Pentavalent Human–Bovine (WC3) Reassortant Rotavirus Vaccine

Published in New England Journal of Medicine • Jan 4, 2006

Authors:

Timo Vesikari

David O. Matson

Penelope H. Dennehy

Abstract

BACKGROUND: Rotavirus is a leading cause of childhood gastroenteritis and death worldwide. METHODS: We studied healthy infants approximately 6 to 12 weeks old who were randomly assigned to receive three oral doses of live pentavalent human-bovine (WC3 strain) reassortant rotavirus vaccine containing...

Subject

Medicine

Rotavirus vaccine

Rotavirus

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