Classical Hodgkin lymphoma is characterized by recurrent copy number gains of the short arm of chromosome 2

Joos, Stefan; K. Menz, Christiane; Wrobel, Gunnar; Siebert, Reiner; Gesk, Stefan; Öhl, S.; Mechtersheimer, Gunhild; Trümper, Lorenz; Mӧller, Peter; Lichter, Peter; F.E. Barth, Thomas

doi:10.1182/blood.v99.4.1381

Public

Classical Hodgkin lymphoma is characterized by recurrent copy number gains of the short arm of chromosome 2

Published in Blood • Feb 15, 2002

Authors:

Stefan Joos

Christiane K. Menz

Gunnar Wrobel

Abstract

Hodgkin- and Reed-Sternberg (HRS) cells microdissected from 41 classical Hodgkin lymphomas (cHL) of 40 patients comprising 8 lymphocyte-rich (cHL-LR), 16 nodular sclerosis (cHL-NS), 15 mixed-cellularity (cHL-MC), and 2 lymphocyte-depletion (cHL-LD) subtypes were analyzed by comparative genomic hybri...

Subject

Fluorescence in situ hybridization

Nodular sclerosis

Biology

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