Bevacizumab in Combination With Oxaliplatin-Based Chemotherapy As First-Line Therapy in Metastatic Colorectal Cancer: A Randomized Phase III Study

B. Saltz, Leonard; Clarke, Stephen; Díaz‐Rubio, Eduardo; Scheithauer, Werner; Figer, Arié; Wong, Ralph; Koski, Sheryl; Lichinitser, Mikhail; Yang, Tsai‐Shen; Rivera, Fernando; Couture, Félix; Sirzén, Florin; Cassidy, Jim

doi:10.1200/jco.2007.14.9930

Public

Bevacizumab in Combination With Oxaliplatin-Based Chemotherapy As First-Line Therapy in Metastatic Colorectal Cancer: A Randomized Phase III Study

Published in Journal of Clinical Oncology • Apr 17, 2008

Authors:

Leonard B. Saltz

Stephen Clarke

Eduardo Díaz‐Rubio

Abstract

PURPOSE: To evaluate the efficacy and safety of bevacizumab when added to first-line oxaliplatin-based chemotherapy (either capecitabine plus oxaliplatin [XELOX] or fluorouracil/folinic acid plus oxaliplatin [FOLFOX-4]) in patients with metastatic colorectal cancer (MCRC). PATIENTS AND METHODS: Pati...

Subject

Bevacizumab

Medicine

Oxaliplatin

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