Dysfunction of the intestinal microbiome in inflammatory bowel disease and treatment

C. Morgan, Xochitl; L. Tickle, Timothy; Sokol, Harry; Gevers, Dirk; L. Devaney, Kathryn; V. Ward, Doyle; A Reyes, Joshua; A. Shah, Shiraz; S. LeLeiko, Neal; B. Snapper, Scott; Bousvaros, Athos; R. Korzenik, Joshua; E. Sands, Bruce; J. Xavier, Ramnik; Huttenhower, Curtis

doi:10.1186/gb-2012-13-9-r79

Public

Dysfunction of the intestinal microbiome in inflammatory bowel disease and treatment

Published in Genome biology • Sep 26, 2012

Authors:

Xochitl C. Morgan

Timothy L. Tickle

Harry Sokol

Abstract

BACKGROUND: The inflammatory bowel diseases (IBD) Crohn's disease and ulcerative colitis result from alterations in intestinal microbes and the immune system. However, the precise dysfunctions of microbial metabolism in the gastrointestinal microbiome during IBD remain unclear. We analyzed the micro...

Subject

Biology

Metagenomics

Microbiome

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