Safety and efficacy of granulocyte and monocyte adsorption apheresis in patients with active ulcerative colitis: A multicenter study

Shimoyama, Takashi; Sawada, Koji; Hiwatashi, Nobuo; Sawada, Toshio; Matsueda, Kei; Munakata, Akihiro; Asakura, Hitoshi; Tanaka, Takao; Kasukawa, Reiji; Kimura, Ken; Suzuki, Yasuo; Nagamachi, Yukio; Muto, Tetsuichiro; Nagawa, Hirokazu; Iizuka, Bun‐ei; Baba, Shozo; Nasu, Masaru; Kataoka, Tatsuji; Kashiwagi, Nobuhito; R. Saniabadi, Abby

doi:10.1002/jca.1000

Public

Safety and efficacy of granulocyte and monocyte adsorption apheresis in patients with active ulcerative colitis: A multicenter study

Published in Journal of Clinical Apheresis • Jan 1, 2001

Authors:

Takashi Shimoyama

Koji Sawada

Nobuo Hiwatashi

Abstract

Active ulcerative colitis (UC) is characterized by activation and infiltration of granulocytes and monocytes/macrophages into the colonic mucosa. The infiltrated leukocytes can cause mucosal damage by releasing degradative proteases, reactive oxygen derivatives, and proinflammatory cytokines. The ai...

Subject

Medicine

Apheresis

Prednisolone

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