THE THERAPEUTIC EFFECTS OF AN ENGINEERED HUMAN ANTI-TUMOUR NECROSIS FACTOR ALPHA ANTIBODY (CDP571) IN RHEUMATOID ARTHRITIS

Rankin, E.C.C.; Choy, Ernest; Kassimos, Dimitrios; Kingsley, Gabrielle; M. SOPWTTH, A.; Isenberg, David; S Panayi, G

doi:10.1093/rheumatology/34.4.334

Public

THE THERAPEUTIC EFFECTS OF AN ENGINEERED HUMAN ANTI-TUMOUR NECROSIS FACTOR ALPHA ANTIBODY (CDP571) IN RHEUMATOID ARTHRITIS

Published in Lara D. Veeken • Jan 1, 1995

Authors:

E.C.C. Rankin

Ernest Choy

Dimitrios Kassimos

Abstract

Pro-inflammatory cytokines such as tumour necrosis factor alpha (TNF alpha) have been implicated in the pathogenesis of rheumatoid arthritis (RA), and have therefore become therapeutic targets. An engineered human antibody, CDP571, that neutralizes human TNF alpha was administered intravenously in s...

Subject

Medicine

Rheumatoid arthritis

Erythrocyte sedimentation rate

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