The t(8;9)(p22;p24) Is a Recurrent Abnormality in Chronic and Acute Leukemia that Fuses <i>PCM1</i> to <i>JAK2</i>

Reiter, Andreas; Walz, Christoph; E. Watmore, A.; Schoch, Claudia; Blau, Ilona; Schlegelberger, Brigitte; Berger, Ute; Telford, Nick; Aruliah, Shilani; A. Liu Yin, John; Vanstraelen, Danny; F. Barker, Helen; C. Taylor, Peter; O’Driscoll, Aisling; Benedetti, Fabio; Rudolph, Cornelia; Kolb, Hans‐Jochem; Hochhaus, Andreas; Hehlmann, Rüdiger; Chase, Andrew; C.P. Cross, Nicholas

doi:10.1158/0008-5472.can-04-4263

Public

The t(8;9)(p22;p24) Is a Recurrent Abnormality in Chronic and Acute Leukemia that Fuses PCM1 to JAK2

Published in Cancer Research • Apr 1, 2005

Authors:

Andreas Reiter

Christoph Walz

A. E. Watmore

Abstract

We have identified a t(8;9)(p21-23;p23-24) in seven male patients (mean age 50, range 32-74) with diverse hematologic malignancies and clinical outcomes: atypical chronic myeloid leukemia/chronic eosinophilic leukemia (n = 5), secondary acute myeloid leukemia (n = 1), and pre-B-cell acute lymphoblas...

Subject

Myeloid leukemia

Fusion gene

Biology

Finding related papers...

Discussions

(0)

No comments yet

Be the first to share your thoughts!