Triple-Negative Breast Cancer: Distinguishing between Basal and Nonbasal Subtypes

A. Rakha, Emad; Elsheikh, Somaia; A. Aleskandarany, Mohammed; O. Habashi, Hany; R. Green, Andrew; G. Powe, Desmond; E. El‐Sayed, Maysa; Benhasouna, Ahmed; Brunet, Jean‐Sébastien; A. Akslen, Lars; Evans, Andy; W. Blamey, Roger; S. Reis‐Filho, Jorge; D. Foulkes, William; O. Ellis, Ian

doi:10.1158/1078-0432.ccr-08-2132

Public

Triple-Negative Breast Cancer: Distinguishing between Basal and Nonbasal Subtypes

Published in Clinical Cancer Research • Mar 25, 2009

Authors:

Emad A. Rakha

Somaia Elsheikh

Mohammed A. Aleskandarany

Abstract

PURPOSE: Triple-negative (TN; estrogen receptor, progesterone receptor, and HER-2 negative) cancer and basal-like breast cancer (BLBC) are associated with poor outcome and lack the benefit of targeted therapy. It is widely perceived that BLBC and TN tumors are synonymous and BLBC can be defined usin...

Subject

Breast cancer

Oncology

Medicine

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