Triple-Negative Breast Cancer: Distinguishing between Basal and Nonbasal Subtypes

A. Rakha, Emad; E. Elsheikh, Somaia; A. Aleskandarany, Muhammed; O. Habashi, Hany; R. Green, Andrew; G. Powe, Desmond; E. El-Sayed, Maysa; Benhasouna, Ahmed; Brunet, Jean-Sébastien; A. Akslen, Lars; J. Evans, Andy; Blamey, Roger; S. Reis-Filho, Jorge; D. Foulkes, William; O. Ellis, Ian

doi:10.1158/1078-0432.ccr-08-2132

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Triple-Negative Breast Cancer: Distinguishing between Basal and Nonbasal Subtypes

Shared by NobleBlocks on Apr 1, 2009 • 12:00 AM UTC

Authors:

Emad A. Rakha

Somaia E. Elsheikh

Muhammed A. Aleskandarany

Abstract

Abstract Purpose: Triple-negative (TN; estrogen receptor, progesterone receptor, and HER-2 negative) cancer and basal-like breast cancer (BLBC) are associated with poor outcome and lack the benefit of targeted therapy. It is widely perceived that BLBC and TN tumors are synonymous and BLBC can be def...

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