Research Strategies for Safety Evaluation of Nanomaterials, Part V: Role of Dissolution in Biological Fate and Effects of Nanoscale Particles

J. A. Borm, Paul; C. Klaessig, Frederick; D. Landry, Timothy; Moudgil, Brij; Pauluhn, Jürgen; Thomas, Karluss; Trottier, Remi; P. Wood, Stewart

doi:10.1093/toxsci/kfj084

Public

Research Strategies for Safety Evaluation of Nanomaterials, Part V: Role of Dissolution in Biological Fate and Effects of Nanoscale Particles

Published in Toxicological Sciences • Jan 4, 2006

Authors:

Paul J. A. Borm

Frederick C. Klaessig

Timothy D. Landry

Abstract

Dissolution, translocation, and disposition have been shown to play a key role in the fate and effects of inhaled particles and fibers. Concepts that have been applied in the micron size range may be usefully applied to the nanoscale range, but new challenges are presented based on the small size an...

Subject

Dissolution

Nanoscopic scale

Particle size

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