Arginine-16  2 adrenoceptor genotype predisposes to exacerbations in young asthmatics taking regular salmeterol

N A Palmer, C; J. Lipworth, Brian; Lun Lee, So; Ismail, Tahmina; MacGregor, David; Mukhopadhyay, Somnath

doi:10.1136/thx.2006.059386

Public

Arginine-16 2 adrenoceptor genotype predisposes to exacerbations in young asthmatics taking regular salmeterol

Published in Thorax • Jun 14, 2006

Authors:

C N A Palmer

Brian J. Lipworth

So Lun Lee

Abstract

BACKGROUND: The homozygous presence of the arginine-16 variant of the beta(2) adrenoceptor gene ADRB2 reverses the benefits from the regular use of short acting beta(2) agonists in asthmatic adults compared with the homozygous glycine-16 genotype. We studied the effect of this polymorphic variation ...

Subject

Medicine

Salmeterol

Bronchodilator Agents

Research Assistant

AI chat, annotations, notes & similar papers

Finding related papers...

Discussions

(0)

No comments yet

Be the first to share your thoughts!