Quantitative bioimaging by LA-ICP-MS: a methodological study on the distribution of Pt and Ru in viscera originating from cisplatin- and KP1339-treated mice

Egger, Alexander; Theiner, Sarah; Kornauth, Christoph; Heffeter, Petra; Berger, Walter; K. Keppler, Bernhard; G. Hartinger, Christian

doi:10.1039/c4mt00072b

Public

Quantitative bioimaging by LA-ICP-MS: a methodological study on the distribution of Pt and Ru in viscera originating from cisplatin- and KP1339-treated mice

Published in Metallomics • Jan 1, 2014

Authors:

Alexander Egger

Sarah Theiner

Christoph Kornauth

Abstract

Laser ablation-inductively coupled plasma-mass spectrometry (LA-ICP-MS) was used to study the spatially-resolved distribution of ruthenium and platinum in viscera (liver, kidney, spleen, and muscle) originating from mice treated with the investigational ruthenium-based antitumor compound KP1339 or c...

Subject

Cisplatin

Distribution (mathematics)

Chemistry

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