Pancreatic stellate cells: partners in crime with pancreatic cancer cells.

A, Vonlaufen; S, Joshi; C, Qu; PA, Phillips; Z, Xu; NR, Parker; CS, Toi; RC, Pirola; JS, Wilson; D, Goldstein; MV, Apte

doi:10.1158/0008-5472.can-07-2477

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Pancreatic stellate cells: partners in crime with pancreatic cancer cells.

Shared by NobleBlocks on Apr 1, 2008 • 12:00 AM UTC

Authors:

Vonlaufen A

Joshi S

Qu C

Abstract

Pancreatic stellate cells (PSC) produce the stromal reaction in pancreatic cancer, but their role in cancer progression is not fully elucidated. We examined the influence of PSCs on pancreatic cancer growth using (a) an orthotopic model of pancreatic cancer and (b) cultured human PSCs (hPSC) and hum...

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