Immunization with Recombinant Brucella Species Outer Membrane Protein Omp16 or Omp19 in Adjuvant Induces Specific CD4 + and CD8 + T Cells as Well as Systemic and Oral Protection against Brucella abortus Infection

A. Pasquevich, Karina; M. Estein, Silvia; García Samartino, Clara; Zwerdling, Astrid; M. Coria, Lorena; Barrionuevo, Paula; A. Fossati, Carlos; H. Giambartolomei, Guillermo; Cassataro, Juliana

doi:10.1128/iai.01151-08

Public

Immunization with Recombinant Brucella Species Outer Membrane Protein Omp16 or Omp19 in Adjuvant Induces Specific CD4 + and CD8 + T Cells as Well as Systemic and Oral Protection against Brucella abortus Infection

Published in Infection and Immunity • Nov 3, 2008

Authors:

Karina A. Pasquevich

Silvia M. Estein

Clara García Samartino

Abstract

Available vaccines against Brucella spp. are live attenuated Brucella strains. In order to engineer a better vaccine to be used in animals and humans, our laboratory aims to develop an innocuous subunit vaccine. Particularly, we are interested in the outer membrane proteins (OMPs) of B. abortus: Omp...

Subject

Adjuvant

Immunization

Biology

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