Postoperative Concurrent Radiotherapy and Chemotherapy for High-Risk Squamous-Cell Carcinoma of the Head and Neck

S. Cooper, Jay; F. Pajak, Thomas; A. Forastiere, Arlene; Jacobs, John; H. Campbell, Bruce; Saxman, Scott; A. Kish, Julie; E. Kim, Harold; J. Cmelak, Anthony; Rotman, Marvin; Machtay, Mitchell; F. Ensley, John; S. Clifford Chao, K.; J. Schultz, Christopher; Y. Lee, Nancy; K. Fu, Karen

doi:10.1056/nejmoa032646

Public

Postoperative Concurrent Radiotherapy and Chemotherapy for High-Risk Squamous-Cell Carcinoma of the Head and Neck

Published in New England Journal of Medicine • May 5, 2004

Authors:

Jay S. Cooper

Thomas F. Pajak

Arlene A. Forastiere

Abstract

BACKGROUND: Despite the use of resection and postoperative radiotherapy, high-risk squamous-cell carcinoma of the head and neck frequently recurs in the original tumor bed. We tested the hypothesis that concurrent postoperative administration of cisplatin and radiotherapy would improve the rate of l...

Subject

Medicine

Radiation therapy

Cisplatin

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