Cathepsin L deficiency as molecular defect of <i>furless:</i> hyperproliferation of keratinocytes and pertubation of hair follicle cycling

Roth, Wera; M. Deussing, Jan; A. Botchkarev, Vladimir; Pauly-Evers, Meike; Säftig, Paul; Hafner, Angela; Schmidt, Péter; W. Schmahl, Wolfgang; Scherer, Johanna; Anton‐Lamprecht, I.; Von Figura, Kurt; Paus, Ralf; Peters, Christoph

doi:10.1096/fj.99-0970com

Public

Cathepsin L deficiency as molecular defect of furless: hyperproliferation of keratinocytes and pertubation of hair follicle cycling

Published in The FASEB Journal • Oct 1, 2000

Authors:

Wera Roth

Jan M. Deussing

Vladimir A. Botchkarev

Abstract

ABSTRACT Lysosomal cysteine proteinases of the papain family are involved in lysosomal bulk proteolysis, major histocompatibility complex class II mediated antigen presentation, prohormone processing, and extracellular matrix remodeling. Cathepsin L (CTSL) is a ubiquitously expressed major represent...

Subject

Hair follicle

Cycling

Follicle

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