MECHANISM OF BONE FORMATION WITH GENE TRANSFER OF THE CDNA ENCODING FOR THE INTRACELLULAR PROTEIN LMP-1

BACKGROUND: LIM mineralization protein-1 (LMP-1), an intracellular protein, is thought to induce secretion of soluble factors that convey its osteoinductive activity. Although evidence suggests that LMP-1 may be a critical regulator of osteoblast differentiation in vitro and in vivo, little is known... View More