Relationship of BMPR2 mutations to vasoreactivity in pulmonary arterial hypertension.

CG, Elliott; EW, Glissmeyer; GT, Havlena; J, Carlquist; JT, McKinney; S, Rich; MD, McGoon; MB, Scholand; M, Kim; RL, Jensen; JW, Schmidt; K, Ward

doi:10.1161/circulationaha.105.601930

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Relationship of BMPR2 mutations to vasoreactivity in pulmonary arterial hypertension.

Shared by NobleBlocks on May 22, 2006 • 12:00 AM UTC

Authors:

Elliott CG

Glissmeyer EW

Havlena GT

Abstract

Background Vasoreactivity tests are fundamental in evaluating pulmonary arterial hypertension (PAH). Mutations of the transforming growth factor-beta type II receptor gene, BMPR2, predispose to the development of pulmonary hypertension and may alter the response to vasodilators. Previous investigati...

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