Diagnosis of Childhood Tuberculosis and Host RNA Expression in Africa

T. Anderson, Suzanne; Kaforou, Myrsini; Brent, Andrew; Wright, Victoria; M. Banwell, Claire; Chagaluka, George; C. Crampin, Amelia; M. Dockrell, Hazel; French, Neil; Shea Hamilton, Melissa; L. Hibberd, Martin; Kern, Florian; R. Langford, Paul; Ling, Ling; Mlotha, Rachel; H. M. Ottenhoff, Tom; Pienaar, Sandy; Pillay, Vashini; Anthony G. Scott, J.; Twahir, Hemed; J. Wilkinson, Robert; Coin, Lachlan; S. Heyderman, Robert; Levin, Michael; Eley, Brian

doi:10.1056/nejmoa1303657

Public

Diagnosis of Childhood Tuberculosis and Host RNA Expression in Africa

Published in New England Journal of Medicine • Apr 30, 2014

Authors:

Suzanne T. Anderson

Myrsini Kaforou

Andrew Brent

Abstract

BACKGROUND: Improved diagnostic tests for tuberculosis in children are needed. We hypothesized that transcriptional signatures of host blood could be used to distinguish tuberculosis from other diseases in African children who either were or were not infected with the human immunodeficiency virus (H...

Subject

Tuberculosis

Medicine

Human immunodeficiency virus (HIV)

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