Novel biomarkers for pre-diabetes identified by metabolomics.

Wang-Sattler, Rui; Yu, Zhonghao; Herder, Christian; C Messias, Ana; Floegel, Anna; He, Ying; Heim, Katharina; Campillos, Monica; Holzapfel, Christina; Thorand, Barbara; Grallert, Harald; Xu, Tao; Bader, Erik; Huth, Cornelia; Mittelstrass, Kirstin; Döring, Angela; Meisinger, Christa; Gieger, Christian; Prehn, Cornelia; Roemisch-Margl, Werner; Carstensen, Maren; Xie, Lu; Yamanaka-Okumura, Hisami; Xing, Guihong; Ceglarek, Uta; Thiery, Joachim; Giani, Guido; Lickert, Heiko; Lin, Xu; Li, Yixue; Boeing, Heiner; Joost, Hans-Georg; Hrabé de Angelis, Martin; Rathmann, Wolfgang; Suhre, Karsten; Prokisch, Holger; Peters, Annette; Meitinger, Thomas; Roden, Michael; Wichmann, H-Erich; Pischon, Tobias; Adamski, Jerzy; Illig, Thomas

doi:10.1038/msb.2012.43

Public

Novel biomarkers for pre-diabetes identified by metabolomics.

Shared by NobleBlocks on Jan 1, 2012 • 12:00 AM UTC

Authors:

Rui Wang-Sattler

Zhonghao Yu

Christian Herder

Abstract

Type 2 diabetes (T2D) can be prevented in pre-diabetic individuals with impaired glucose tolerance (IGT). Here, we have used a metabolomics approach to identify candidate biomarkers of pre-diabetes. We quantified 140 metabolites for 4297 fasting serum samples in the population-based Cooperative Heal...

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