Infectivity, Transmission, and Pathology of Human-Isolated H7N9 Influenza Virus in Ferrets and Pigs

Zhu, Huachen; Wang, D.; J. Kelvin, David; Li, Long; Zheng, Zongtai; Yoon, Sun‐Woo; Wong, Sook‐San; Farooqui, Amber; Wang, J.; W. Banner, David; Chen, R.; Zheng, Ruifeng; Zhou, Jun; Zhang, Yulin; Hong, W.; Dong, Wei; Cai, Qixu; H. A. Roehrl, Michael; S. H. Huang, Stephen; A. Kelvin, Alyson; Yao, T.; Zhou, Biao; Chen, X.; Leung, GM; L. M. Poon, Leo; G. Webster, Robert; J. Webby, Richard; Peiris, Malik; Guan, Yi; Shu, Yuelong

doi:10.1126/science.1239844

Public

Infectivity, Transmission, and Pathology of Human-Isolated H7N9 Influenza Virus in Ferrets and Pigs

Published in Science • May 24, 2013

Authors:

Huachen Zhu

D. Wang

David J. Kelvin

Abstract

The emergence of the H7N9 influenza virus in humans in Eastern China has raised concerns that a new influenza pandemic could occur. Here, we used a ferret model to evaluate the infectivity and transmissibility of A/Shanghai/2/2013 (SH2), a human H7N9 virus isolate. This virus replicated in the upper...

Subject

Infectivity

Virology

Virus

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