Infectivity, transmission, and pathology of human-isolated H7N9 influenza virus in ferrets and pigs.

Zhu, H; Wang, D; J Kelvin, D; Li, L; Zheng, Z; Yoon, S-W; Wong, S-S; Farooqui, A; Wang, J; Banner, D; Chen, R; Zheng, R; Zhou, J; Zhang, Y; Hong, W; Dong, W; Cai, Q; H A Roehrl, M; S H Huang, S; A Kelvin, A; Yao, T; Zhou, B; Chen, X; M Leung, G; L M Poon, L; G Webster, R; J Webby, R; S M Peiris, J; Guan, Y; Shu, Y

doi:10.1126/science.1239844

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Infectivity, transmission, and pathology of human-isolated H7N9 influenza virus in ferrets and pigs.

Shared by NobleBlocks on Jul 12, 2013 • 12:00 AM UTC

Authors:

H Zhu

D Wang

D J Kelvin

Abstract

The emergence of the H7N9 influenza virus in humans in Eastern China has raised concerns that a new influenza pandemic could occur. Here, we used a ferret model to evaluate the infectivity and transmissibility of A/Shanghai/2/2013 (SH2), a human H7N9 virus isolate. This virus replicated in the upper...

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