Final Trial Report of Sentinel-Node Biopsy versus Nodal Observation in Melanoma

L. Morton, Donald; F. Thompson, John; J. Cochran, Alistair; Mozzillo, Nicola; E. Nieweg, Omgo; F. Roses, Daniel; Hoekstra, H.J.; P. Karakousis, Constantine; A. Puleo, Christopher; J. Coventry, Brendon; Kashani–Sabet, Mohammed; Mark Smithers, B.; Paul, Eberhard; Kraybill, William; Gregory McKinnon, J.; Wang, He-Jing; M. Elashoff, Robert; B. Faries, Mark

doi:10.1056/nejmoa1310460

Public

Final Trial Report of Sentinel-Node Biopsy versus Nodal Observation in Melanoma

Published in New England Journal of Medicine • Feb 12, 2014

Authors:

Donald L. Morton

John F. Thompson

Alistair J. Cochran

Abstract

BACKGROUND: Sentinel-node biopsy, a minimally invasive procedure for regional melanoma staging, was evaluated in a phase 3 trial. METHODS: We evaluated outcomes in 2001 patients with primary cutaneous melanomas randomly assigned to undergo wide excision and nodal observation, with lymphadenectomy fo...

Subject

Medicine

Hazard ratio

Biopsy

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