High Circulating Levels of the Dengue Virus Nonstructural Protein NS1 Early in Dengue Illness Correlate with the Development of Dengue Hemorrhagic Fever

H. Libraty, Daniel; R. Young, Paul; Pickering, Darren; P. Endy, Timothy; Kalayanarooj, Siripen; Green, Sharone; W. Vaughn, David; Nisalak, Ananda; A Ennis, F; L. Rothman, Alan

doi:10.1086/343813

Public

High Circulating Levels of the Dengue Virus Nonstructural Protein NS1 Early in Dengue Illness Correlate with the Development of Dengue Hemorrhagic Fever

Published in The Journal of Infectious Diseases • Oct 8, 2002

Authors:

Daniel H. Libraty

Paul R. Young

Darren Pickering

Abstract

Infection with any 1 of 4 dengue viruses produces a spectrum of clinical illness ranging from a mild undifferentiated febrile illness to dengue fever (DF) to dengue hemorrhagic fever (DHF), a potentially life-threatening disease. The morbidity and mortality of DHF can be reduced by early hospitaliza...

Subject

Dengue fever

Dengue virus

Viremia

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