Effect of very high-intensity statin therapy on regression of coronary atherosclerosis: the ASTEROID trial.

SE, Nissen; SJ, Nicholls; I, Sipahi; P, Libby; JS, Raichlen; CM, Ballantyne; J, Davignon; R, Erbel; JC, Fruchart; JC, Tardif; P, Schoenhagen; T, Crowe; V, Cain; K, Wolski; M, Goormastic; EM, Tuzcu

doi:10.1001/jama.295.13.jpc60002

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Effect of very high-intensity statin therapy on regression of coronary atherosclerosis: the ASTEROID trial.

Shared by NobleBlocks on Mar 13, 2006 • 12:00 AM UTC

Authors:

Nissen SE

Nicholls SJ

Sipahi I

Abstract

Context Prior intravascular ultrasound (IVUS) trials have demonstrated slowing or halting of atherosclerosis progression with statin therapy but have not shown convincing evidence of regression using percent atheroma volume (PAV), the most rigorous IVUS measure of disease progression and regression....

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