Molecular Detection of FUS-CREB3L2 Fusion Transcripts in Low-grade Fibromyxoid Sarcoma Using Formalin-fixed, Paraffin-embedded Tissue Specimens

Matsuyama, Atsuji; Hisaoka, Masanori; Shimajiri, Shohei; Hayashi, Tomayoshi; Imamura, Tetsuo; Ishida, Tsuyoshi; Fukunaga, Masaharu; Fukuhara, Toshiyuki; Minato, Hiroshi; Nakajima, Takashi; Yonezawa, Suguru; Kuroda, Makoto; Yamasaki, Fumio; Toyoshima, Satoshi; Hashimoto, Hiroshi

doi:10.1097/01.pas.0000209830.24230.1f

Public

Molecular Detection of FUS-CREB3L2 Fusion Transcripts in Low-grade Fibromyxoid Sarcoma Using Formalin-fixed, Paraffin-embedded Tissue Specimens

Published in The American Journal of Surgical Pathology • Aug 21, 2006

Authors:

Atsuji Matsuyama

Masanori Hisaoka

Shohei Shimajiri

Abstract

A diagnosis of low-grade fibromyxoid sarcoma (LGFMS) remains problematic because of its bland-looking histologic features that can be potentially confused with other benign or low-grade fibromyxoid lesions. Recent cytogenetic and molecular analyses have shown that most LGFMSs have a characteristic c...

Subject

Fusion gene

Biology

Sarcoma

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