PROACT: A Phase II Randomized Trial of Recombinant Pro-Urokinase by Direct Arterial Delivery in Acute Middle Cerebral Artery Stroke

J. del Zoppo, Gregory; T. Higashida, Randall; J. Furlan, Anthony; S. Pessin, Michael; A. Rowley, Howard; Gent, Michael

doi:10.1161/01.str.29.1.4

Public

PROACT: A Phase II Randomized Trial of Recombinant Pro-Urokinase by Direct Arterial Delivery in Acute Middle Cerebral Artery Stroke

Published in Stroke • Jan 1, 1998

Authors:

Gregory J. del Zoppo

Randall T. Higashida

Anthony J. Furlan

Abstract

BACKGROUND AND PURPOSE: To test the safety and recanalization efficacy of intra-arterial local delivery of plasminogen activators in acute ischemic stroke, a randomized trial of recombinant pro-urokinase (rpro-UK) versus placebo was undertaken in patients with angiographically documented proximal mi...

Subject

Medicine

Thrombolysis

Urokinase

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