Trastuzumab plus Adjuvant Chemotherapy for Operable HER2-Positive Breast Cancer

H. Romond, Edward; A. Perez, Edith; Bryant, John; J. Suman, Vera; E. Geyer, Charles; E. Davidson, Nancy; Tan-Chiu, Elizabeth; Martino, Silvana; Paik, Soonmyung; A. Kaufman, Peter; M. Swain, Sandra; M. Pisansky, Thomas; Fehrenbacher, Louis; A. Kutteh, Leila; G. Vogel, Victor; W. Visscher, Daniel; Yothers, Greg; B. Jenkins, Robert; Brown, Ann; R. Dakhil, Shaker; P. Mamounas, Eleftherios; L. Lingle, Wilma; Klein, Pamela; N. Ingle, James; Wolmark, Norman

doi:10.1056/nejmoa052122

Public

Trastuzumab plus Adjuvant Chemotherapy for Operable HER2-Positive Breast Cancer

Published in New England Journal of Medicine • Oct 20, 2005

Authors:

Edward H. Romond

Edith A. Perez

John Bryant

Abstract

BACKGROUND: We present the combined results of two trials that compared adjuvant chemotherapy with or without concurrent trastuzumab in women with surgically removed HER2-positive breast cancer. METHODS: The National Surgical Adjuvant Breast and Bowel Project trial B-31 compared doxorubicin and cycl...

Subject

Medicine

Trastuzumab

Oncology

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