Azithromycin for prevention of exacerbations in severe asthma (AZISAST): a multicentre randomised double-blind placebo-controlled trial

Brusselle, Guy; VanderStichele, Christine; Jordens, Paul; DEMAN, R; Slabbynck, Hans; Ringoet, Veerle; M. Verleden, Geert; Demedts, Ingel; Verhamme, Katia; Delporte, Anja; Demeyere, Bénédicte; Claeys, Geert; Boelens, Jerina; Padalko, Elizaveta; Verschakelen, Johny; Van Maele, Georges; Deschepper, Ellen; Joos, Guy

doi:10.1136/thoraxjnl-2012-202698

Public

Azithromycin for prevention of exacerbations in severe asthma (AZISAST): a multicentre randomised double-blind placebo-controlled trial

Published in Thorax • Jan 3, 2013

Authors:

Guy Brusselle

Christine VanderStichele

Paul Jordens

Abstract

BACKGROUND: Patients with severe asthma are at increased risk of exacerbations and lower respiratory tract infections (LRTI). Severe asthma is heterogeneous, encompassing eosinophilic and non-eosinophilic (mainly neutrophilic) phenotypes. Patients with neutropilic airway diseases may benefit from ma...

Subject

Medicine

Azithromycin

Placebo

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