Genome-Wide Association Study for Coronary Artery Calcification With Follow-Up in Myocardial Infarction

J. O’Donnell, Christopher; Kavousi, Maryam; V. Smith, Albert; L. R. Kardia, Sharon; F. Feitosa, Mary; Hwang, Shih-Jen; V. Sun, Yan; A. Province, Michael; Aspelund, Thor; Dehghan, Abbas; Hoffmann, Udo; F. Bielak, Lawrence; Zhang, Qunyuan; Eiríksdóttir, Guðný; M. van Duijn, Cornelia; S. Fox, Caroline; de Andrade, Mariza; T. Kraja, Aldi; Sigurðsson, Sigurður; Elias‐Smale, Suzette; M. Murabito, Joanne; J. Launer, Lenore; van der Lugt, Aad; Kathiresan, Sekar; P. Krestin, Gabriël; M. Herrington, David; D. Howard, Timothy; Liu, Ching‐Ti; S. Post, Wendy; D. Mitchell, Braxton; R. O’Connell, Jeffrey; Shen, Haiqing; R. Shuldiner, Alan; Altshuler, David; Elosúa, Roberto; Salomaa, Veikko; M. Schwartz, Stephen; S. Siscovick, David; F. Voight, Benjamin; C. Bis, Joshua; L. Glazer, Nicole; M. Psaty, Bruce; Boerwinkle, Eric; Heiss, Gerardo; Blankenberg, Stefan; Zeller, Tanja; S. Wild, Philipp; B. Schnabel, Renate; Schillert, Arne; Ziegler, Andreas; F. Münzel, Thomas; C. White, Charles; I. Rotter, Jerome; A. Nalls, Michael; Oudkerk, Matthijs; D. Johnson, Andrew; B. Newman, Anne; G. Uitterlinden, André; M. Massaro, Joseph; M. Cunningham, Julie; B. Harris, Tamara; Hofman, Albert; A. Peyser, Patricia; B. Borecki, Ingrid; Adrienne Cupples, L.; Guðnason, Vilmundur; C.M. Witteman, Jacqueline

doi:10.1161/circulationaha.110.974899

Public

Genome-Wide Association Study for Coronary Artery Calcification With Follow-Up in Myocardial Infarction

Published in Circulation • Dec 1, 2011

Authors:

Christopher J. O’Donnell

Maryam Kavousi

Albert V. Smith

Abstract

BACKGROUND: Coronary artery calcification (CAC) detected by computed tomography is a noninvasive measure of coronary atherosclerosis, which underlies most cases of myocardial infarction (MI). We sought to identify common genetic variants associated with CAC and further investigate their associations...

Subject

Genome-wide association study

Single-nucleotide polymorphism

Medicine

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