Polyacrylic acid@zeolitic imidazolate framework-8 nanoparticles with ultrahigh drug loading capability for pH-sensitive drug release

Ren, Hong; Zhang, Lingyu; An, Jiping; Wang, Tingting; Li, Lu; Si, Xiaoyan; Liu, He; Wu, Xiaotong; Wang, Chungang; Su, Zhong‐Min

doi:10.1039/c3cc47666a

Public

Polyacrylic acid@zeolitic imidazolate framework-8 nanoparticles with ultrahigh drug loading capability for pH-sensitive drug release

Published in Chemical Communications • Nov 11, 2013

Authors:

Hong Ren

Lingyu Zhang

Jiping An

Abstract

The polyacrylic acid@zeolitic imidazolate framework-8 (PAA@ZIF-8) nanoparticles (NPs) were first fabricated using a facile and simple route. It is worthwhile noting that the as-fabricated PAA@ZIF-8 NPs possessed ultrahigh doxorubicin (DOX) loading capability (1.9 g DOX g(-1) NPs), which were employe...

Subject

Polyacrylic acid

Zeolitic imidazolate framework

Imidazolate

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