Serum FGF21 Levels Are Increased in Obesity and Are Independently Associated With the Metabolic Syndrome in Humans

Zhang, Xinmei; C.Y. Yeung, Dennis; Karpíšek, Michal; Stejskal, David; Zhou, Zhiguang; Liu, Feng; L.C. Wong, Rachel; Chow, Wing‐Sun; W.K. Tso, Annette; S.L. Lam, Karen; Xu, Aimin

doi:10.2337/db07-1476

Public

Serum FGF21 Levels Are Increased in Obesity and Are Independently Associated With the Metabolic Syndrome in Humans

Published in Diabetes • Feb 5, 2008

Authors:

Xinmei Zhang

Dennis C.Y. Yeung

Michal Karpíšek

Abstract

OBJECTIVE: Fibroblast growth factor 21 (FGF21) is a metabolic regulator with multiple beneficial effects on glucose homeostasis and insulin sensitivity in animal models. This study aimed to investigate the relationship between its serum levels and various cardiometabolic parameters in humans. RESEAR...

Subject

FGF21

Internal medicine

Endocrinology

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