The association between common vitamin D receptor gene variations and osteoporosis: a participant-level meta-analysis.

AG, Uitterlinden; SH, Ralston; ML, Brandi; AH, Carey; D, Grinberg; BL, Langdahl; P, Lips; R, Lorenc; B, Obermayer-Pietsch; J, Reeve; DM, Reid; A, Amedei; A, Bassiti; M, Bustamante; LB, Husted; A, Diez-Perez; H, Dobnig; AM, Dunning; A, Enjuanes; A, Fahrleitner-Pammer; Y, Fang; E, Karczmarewicz; M, Kruk; Leeuwen JP, van; C, Mavilia; Meurs JB, van; J, Mangion; FE, McGuigan; HA, Pols; W, Renner; F, Rivadeneira; Schoor NM, van; S, Scollen; RE, Sherlock; JP, Ioannidis

doi:10.7326/0003-4819-145-4-200608150-00005

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The association between common vitamin D receptor gene variations and osteoporosis: a participant-level meta-analysis.

Shared by NobleBlocks on Aug 1, 2006 • 12:00 AM UTC

Authors:

Uitterlinden AG

Ralston SH

Brandi ML

Abstract

Background Polymorphisms of the vitamin D receptor (VDR) gene have been implicated in the genetic regulation of bone mineral density (BMD). However, the clinical impact of these variants remains unclear.Objective To evaluate the relation between VDR polymorphisms, BMD, and fractures.Design Prospecti...

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