AMPA receptor antibodies in limbic encephalitis alter synaptic receptor location

Lai, Meizan; G. Hughes, Ethan; Peng, Xiaoyu; Zhou, Lei; J. Gleichman, Amy; Shu, Huidy; Matà, Sabrina; Kremens, Daniel; Vitaliani, Roberta; D. Geschwind, Michael; Bataller, Luís; G. Kalb, Robert; Davis, Rebecca; Graus, Francesc; R. Lynch, David; J. Balice‐Gordon, Rita; Dalmau, Josep

doi:10.1002/ana.21589

Public

AMPA receptor antibodies in limbic encephalitis alter synaptic receptor location

Published in Annals of Neurology • Mar 19, 2009

Authors:

Meizan Lai

Ethan G. Hughes

Xiaoyu Peng

Abstract

OBJECTIVE: To report the clinical and immunological features of a novel autoantigen related to limbic encephalitis (LE) and the effect of patients' antibodies on neuronal cultures. METHODS: We conducted clinical analyses of 10 patients with LE. Immunoprecipitation and mass spectrometry were used to ...

Subject

AMPA receptor

Limbic encephalitis

Antibody

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